Renault's F1 boss Flavio Briatore has quit the team just days before a meeting with the FIA over race-fixing allegations
Renault said in a statement that Briatore and director of engineering Pat Symonds had both left the team.
Renault have been summoned to appear before the FIA's International Motor Sport Council in Paris on 21 September to answer claims by Nelson Piquet Junior that he was asked by Renault to crash deliberately during the 2008 Singapore Grand Prix, giving a race-winning advantage to his teammate Spaniard Fernando Alonso.
If Renault are found guilty of race-fixing, they could be expelled from the sport.
The team had denied all of the claims made against them by Piquet junior, who was dismissed by the team in July after being told he had failed to perform to expectations.
But today Renault appeared to partly admit some role in the controversy by adding in the statement they "would not contest the FIA's recent allegations concerning the Singapore Grand Prix".
Italian Briatore led the Renault team to two Formula One constructors' and drivers' championships with Alonso in 2005 and 2006 after also winning titles with Benetton and Michael Schumacher in 1994 and 1995.
Symonds effectively ran the race strategy side and his departure will be a major blow for the team.